Mood Disorders


Dr. Kapczinski has been in the forefront of research in biomarkers for mood disorders. In 2016 his work was recognized in a profile report at Lancet Psychiatry, focusing on his career and achievements.



Dr. Kapczinski and colleagues helped to develop the concepts of neuroprogression and staging in bipolar disorder. He is a coauthor on a recent book called "Neuroprogression in Psychiatry".


Big Data

Our group is advocating for a paradigm shift in clinical neuroscience using artificial intelligence


Our team is building a strong partnership with Pasteur Institute

Some of our

open-access papers

Ascoli BM, Parisi MM, Bristot G, Antqueviezc B, Géa LP, Colombo R, Kapczinski F, Guma FTCR, Brietzke E, Barbé-Tuana FM, Rosa AR. Attenuated inflammatory response of monocyte-derived macrophage from patients with BD: a preliminary report. Int J Bipolar Disord. 2019 Jun 1;7(1):13. doi: 10.1186/s40345-019-0148-x.PubMed PMID: 31152269; PubMed Central PMCID: PMC6544740.

Cho CH, Jung SY, Kapczinski F, Rosa AR, Lee HJ. Validation of the Korean Version of the Biological Rhythms Interview of Assessment in Neuropsychiatry. Psychiatry Investig. 2018 Dec;15(12):1115-1120. doi: 10.30773/pi.2018.10.21.1. Epub 2018 Dec 19. PubMed PMID: 30602104; PubMed Central PMCID: PMC6318494.

Sehmbi M, Rowley CD, Minuzzi L, Kapczinski F, Kwiecien JM, Bock NA, Frey BN. Age-related deficits in intracortical myelination in young adults with bipolar disorder type I. J Psychiatry Neurosci. 2019 Mar 1;44(2):79-88. PubMed PMID: 30525334; PubMed Central PMCID: PMC6397039.

Duarte JA, Massuda R, Goi PD, Vianna-Sulzbach M, Colombo R, Kapczinski F, Gama CS. White matter volume is decreased in bipolar disorder at early and late stages. Trends Psychiatry Psychother. 2018 Oct-Dec;40(4):277-284. doi: 10.1590/2237-6089-2017-0025. PubMed PMID: 30570099.



McMaster University | St. Joseph’s Healthcare

West 5th Campus

Department of Psychiatry and Behavioural Neurosciences

100 West 5th Street

Hamilton, ON, L9C 0E3

Tel: 905.522 1155 x34642